Methods: Male smokers of 20+ pack-years, aged 60 to 74 years, underwent a baseline CXR and sputum cytology examination and received five screening rounds with LDCT or a yearly clinical review only in a randomized fashion.
Measurements and main results: A total of 1,264 subjects were enrolled in the LDCT arm and 1,186 in the control arm. Their median age was 64.0 years (interquartile range, 5), and median smoking exposure was 45.0 pack-years. The median follow-up was 8.35 years. One hundred four patients (8.23%) were diagnosed with lung cancer in the screening arm (66 by CT), 47 of whom (3.71%) had stage I disease; 72 control patients (6.07%) were diagnosed with lung cancer, with 16 (1.35%) being stage I cases. Lung cancer mortality was 543 per 100,000 person-years (95% confidence interval, 413-700) in the LDCT arm versus 544 per 100,000 person-years (95% CI, 410-709) in the control arm (hazard ratio, 0.993; 95% confidence interval, 0.688-1.433).
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Subsequently, the OVR assigned plaintiff to a rehabilitative workshop where he performed individual and team packaging and assembly operations. In a letter dated September 11, 1991 Vocational Counselor Kate DiVittorio reported that during a Personal Adjustment Training ("PAT") period from June 18, 1991 to September 10, 1991, plaintiff was a competent worker, but that he was frequently absent "due to medical appointments." Because plaintiff needed to improve his attendance and strengthen his vocational skills, DiVittorio recommended that plaintiff participate in a second bench assembly PAT.
When the JOIDESResolution arrived in Prydz Bay, the drill site had to be moved to analternate site because pack ice covered much of western Prydz Bay where theprimary site was located. An additional 3-nmi displacement of the site wasrequired because a large tabular iceberg was floating directly over thealternate site. The target sedimentary section was thinner and likely a littleyounger near the base of the section at the final alternate site (i.e., Site1166) than at the primary site. The drilling at Site 1166 was conducted safelyand achieved the desired objective under the sometimes cold and stormy operatingconditions. 041b061a72